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  Aston(RobertShaw),aquiet,reservedman,livesaloneinatop-floorclutteredroomofasmallabandonedhouseinapoorLondondistrict.HebefriendsandtakesinMacDavies(DonaldPleasence),anoldderelictwhohasbeenfiredfromamenialjobinacafé.IntimeAstonoffershimajobascaretakerofthehouse.Aston'sbrother,Mick(AlanBates)-ataunting,quasi-sadist-harassesthederelictwhenhisbrotherisaway,countermandinghisorders.EventuallyAston,himselfirritatedbythecantankerousoldman,putshimouteee
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  In1828Scotland,EdinburghsurgeonDr.KnoxdoesmedicalresearchoncadavershebuysfrommurderersBurkeandHare,withoutquestioningtheunethicalprocurementmethodseee